In Africa, at the continental level, the African Union Commission through its Center for Disease Control developed a continent-wide strategy with two overarching goals of (i) Preventing severe illness and death from COVID-19 infection in Member States, and (ii) Minimizing social disruption and economic consequences of COVID-19 outbreaks. Such actions envisage that the Africa CDC (i) coordinates the efforts of Member States, African Union agencies, World Health Organization, and other partners to ensure synergy and minimize duplication; (ii) promote evidence-based public health practice for surveillance, prevention, diagnosis, treatment, and control of COVID-19.