This Article provides an assessment of the impact of food insecurity and climate change on poverty reduction in the HoA, which is one of the most affected regions in the world by these interlinked challenges. The region is confronted by these interconnected and mutually reinforcing negative conditions, which are compounded by limited institutional constraints, insecurity, and scarce financial resources. Consequently, to end hunger, malnutrition and poverty in all its forms by 2030, it is imperative to implement urgent and radical transformation of food production systems, and to adopt accelerated and scaled up global actions to strengthen the resilience and people's livelihoods in response to climate variability and extremes.